?overexpression

overexpression发音

英：　　美：

overexpression中文意思翻译

n. 超表达

overexpression常见例句

1 、STK15 protein overexpression may be a novel marker for diagnosing tumor differentiation of colorectal cancer.───STK15蛋白过表达程度可望作为判定结肠癌分化程度的新指标。

2 、In EC,COX-2 overexpression was significantly associated with high MVD,and high COX-2 and VEGF expressions had a positive correlation with TNM classification,depth of tumour invasion and lymph node metastasis.───COX-2和VEGF在食管癌组织中出现异常高表达并伴有MVD值增加,而且与肿瘤浸润深度、淋巴结转移和TNM分期呈正相关。

3 、To study the prognostic significance between p53 cDNA mutation measured with RT PCR SSCP and P53 protein overexpression by PAb 1801 monoclonal antibody in 100 cases of colorectal adenocarcinomas.───100份大肠癌组织，用RT－PCR－SSCP检测p53基因cDNA突变；

4 、It is indicated that the expression of E2F1 is increased in the hypertrophic scar and keloid. E2F1 overexpression may play an important role in the proleferation of fibroblasts and in the development of pathological scar.───E2F1基因在病理性瘢痕组织中增高,促进瘢痕组织中修复效应细胞的增生,对病理性瘢痕的形成可能起着重要作用。

5 、Genetic Improvement of Rice for Disease Resistance and Salt Tolerance by Overexpression of OsiWRKY and OPBP1, Two Different Transcription Factors───利用转录因子OsiWRKY和OPBP1基因提高水稻抗病及耐盐性研究

6 、Overexpression of CD_(44)v6,MMP-9Accelerate the Invasion and Metastasis of Gastric Cancer───CD_(44)v6、MMP-9过表达促进胃癌浸润转移

7 、Overexpression of 2 proteins was inhibited significantly during DEN induced hepatcacinogenesis and Brd U LI was reduced strikingly in later stage of model by 981208 agent.───9812 0 8冲剂可明显抑制诱癌过程中两蛋白的**表达 ,显著降低诱癌后期Brd- U细胞标记指数。

8 、Overexpression of p27~(KIP1) induced by Bak gene leads to the arrest in G_1 phase of HCC-9204 cell line───Bak基因诱导P27~(KIP1)基因的过表达使HCC-9204细胞在G_1期停滞

9 、Effects of bax overexpression on expression of bak and bcl-xl in cultured human RPE cells───Bax过表达对培养人视网膜色素上皮细胞bak和bcl-xl表达的影响

10 、The overexpression of ILK and MMP-9 genes may play an important role in the oncogenesis and development of NSCLC respectively.───ILK和MMP-9蛋白过度表达可能分别在NSCLC的发生和发展过程中起重要作用。

11 、Overexpression of P53 Protein in Primary Cholecystic Carcinoma amd Its Clinical Value───原发性胆囊癌P53过度表达及临床意义

12 、The Effect of cdk-5 Overexpression on Neurofilament Phosphorylation───cdk-5过度表达对神经细丝**酸化的影响

13 、P53 is an important tumor suppressor. Abnormal structure and overexpression of C-met and mutation of P53 areclosed associated with the genesis and development of many humancarcinomas.───P53 是重要的肿瘤抑制基因,C-met 基因表达与结构的异常及 P53 基因的突变和多种人类肿瘤的发生、发展密切相关。

14 、Chromosomally mediated multidrug resistance in Salmonella typhimurium is generally attributed to the overexpression of the acrAB locus and the mutation in topoisomerase genes.───AcrAB外流泵系统的过度表达和拓扑异构酶基因突变是导致鼠伤寒沙门菌产生多重耐药性 (MAR)的重要原因。

15 、Tumor growth can be promoted by PDGF via autocrine stimulation of malignant cells, overexpression or overactivation of PDGFRs, or stimulation of angiogenesis within the tumor.───PDGF在肿瘤中的自分泌刺激、PDGFR的过表达或过度活化或者刺激肿瘤内血管生成都会促进肿瘤生长；

16 、A 10 MOI of recombinant nonreplicating adenovirus was found to infect more than 90% of HOS cells within 24 hours by EGFP fluorescence, in which the MPG overexpression and MPG enzyme activity were also detected.───10个感染增殖指数(MOI)的Ad5HA-MPG可使90%以上HOS感染,感染细胞高表达MPG并具有MPG酶活性。

17 、The overexpression of CD44V6 and Bcl-2 may be l inked to the pathogenesis, development and metastasis of cervical carcinoma. Det ermination of CD44V6 and Bcl-2 may be useful for properly estimating the progno sis of cervical carcinoma.───CD44V6、Bcl 2表达与宫颈癌的发生 ,发展及转移密切相关 ,可作为预测宫颈癌预后的辅助指标

18 、EFFECT OF CDK-5 OVEREXPRESSION ON TAU PHOSPHORYLATION───Cdk-5过度表达对Tau蛋白**酸化的影响

19 、Cloning and Overexpression of Prokaryotic Ribonucleic acid enzyme HII in Escherichia coli───原核生物核糖核酸酶HII基因的克隆及在大肠杆菌中的高效表达

20 、In two kidney-one clip hypertensive rats, overexpression of ERK-2 and activated c-jun were associated with the VSMC proliferation in renal arteries.───两肾一夹型高血压时 ,可出现ERK 2过表达 ,转录相关基因c jun活化 ,最终使VSMC增多。

21 、Low-expression of PTEN protein may stimulate overexpression of PI3K protein.───PTEN表达的缺失可能刺激了PI3K蛋白的强**表达。

22 、Most of its manifestations are associated with the overexpression of abnormal immunoglobulin in blood and infiltrative destruction of bone.───其皮肤表现可以分成特异性和非特异性。

23 、When overexpressed of QM, alkalinephosphatase activity and nodule mineralization were both increased in MC3T3-E1from QM overexpression cultures relative to normal expression QM cultures.───为了进一步研究QM基因在成骨细胞骨质形成和代谢中的作用,我们构建了真核表达载体pcDNA3.1/myc-His A/QM并转染到MC3T3-E1中建立过表达QM蛋白的细胞系,研究其表达上调后对细胞的影响。

24 、It is also concluded that human ASPM overexpression is a useful predictive factor for early tumor recurrence after tumor resection, and a prognostic factor associated with poor prognosis.───另外，我们也认为人类ASPM基因的过量表现可以作为一个有效的手术后肿瘤早期再发及预后较差的预测因子。

25 、ASPM overexpression plays important role in the tumor cell proliferation, differentiation, and invasion/metastasis, probably via the downregulation of p27 and upregulation of stathmin.───ASPM基因的过量表现在肿瘤的细胞增殖、细胞分化以及肿瘤侵犯与转移扮演著重要的角色。

26 、Overexpression of JUN after global cerebral ischemia/reperfusion participates in the neural injury procedure and heat shock precondition performes its brain protective function through its suppressive effect on the overexpression of c-jun.───全脑缺血再灌注损伤后JUN蛋白过度表达参与了神经元损伤过程,热休克预处理通过下调JUN蛋白过度表达具有脑保护作用。

27 、The predictor value of HER2/neu overexpression in breast cancer patients with undergoing surgery and CMF adjuvant therapy───HER2/neu表达对乳腺癌术后应用CMF化疗病人预后的影响

28 、Our findings, for the first time, revealed a new biological activity for eIF5A as the regulator of p53. Overexpression of eIF5A or its EFP domain resulted in up-regulation of p53, and silencing eIF5A by siRNA reduced p53 protein level.───eIF5A过表达能导致p53蛋白上调,而eIF5A siRNA则通过抑制内源性eIF5A的表达而下调p53蛋白水平。

29 、Keywords human endostatin;DNA recombination;gene overexpression;───人内皮生长抑素;DNA重组;基因高效表达;

30 、THE RELATIONSHIPS BETWEEN OVEREXPRESSION OF p53 BOTH AND ESOPHAGEAL CANCER(EC) AND THE RISK FACTORS OF EC IN LIN COUNTY───p53高表达与林县食管癌及其危险因素关系的分子流行病学研究

31 、Overexpression of AK fbr gene in C.───AKfbr基因在C.

32 、Hur K,Gazdar AF,Rathi A,et al. Overexpression of human telomerase RNA in Helicobacter pylori-infected human gastric mucosa[J]. Cancer Res, 2000,91 ( 11 ): 1148.───司君利,刘吉勇,元玉琴.幽门螺杆菌感染与胃粘膜端粒酶活性关系的研究[J].世界华人消化杂志,1999,7(5):429.

33 、Keywords periodontitis;osteoprotegerin;OPG;RANKL;alveolar bone overexpression;gene therapy;───关键词牙周炎;骨保护素;OPG;RANKL;骨吸收;基因治疗;

34 、Conclusion: The present study demonstrated HDGF overexpression is correlated with tumor grades, recurrence, proliferation, and tumor immunity in breast cancer.───中文摘要目的:HDGF是一个特殊的生长因子,HDGF在各种癌症的发病过程和预后扮演重要的角色,例如肝癌,胃癌和非小细胞肺癌。

35 、ADRB2 inhibition confers cell invasion and transforms benign prostate epithelial cells, whereas ADRB2 overexpression counteracts EZH2-mediated oncogenesis.───ADRB2受到抑制后促进肿瘤细胞的侵袭和良性的前列腺上皮细胞的转化，因此ADRB2过表达干扰了EZH2调节的肿瘤生成。

36 、The overexpression of COX-2,cyclinD1 in PA and CPA was positively correlated with tumor recurrence and malignant transformation,they probably play an important role in the occurrence and development of CPA in the parotid gland.───COX-2、cyclinD1在PA、CPA中的过表达与肿瘤的复发、恶变有明显关系,二者在PA、CPA的发生发展中可能具有一定的作用。

37 、NFI-A overexpression decreased osteoclast formation and function with down-regulation of M-CSFR levels.───NFI-A的过表达降低破骨细胞的形成，比并抑制其功能，同时伴随着M-CSFR水平的下调。

38 、1) There is overexpression of COX-2 in PC-3m cell line as in PC-3 cell line.───l）同 PC上细胞系一样，PC上m细胞系中存在 COX1 mRNA及蛋白质表达。

39 、The effect of overexpression of Hira on embryogenesis of Drosophila melanogaster───Hira基因的过量表达对果蝇早期胚胎发育的影响

40 、DNR induced overexpression of Pgp in K562/D cells;───DNR诱导了 K5 6 2 / D细胞的 Pgp过度表达。

41 、The loss of PTEN expression is closely related to tumorigenesis and development of the UEC, and the overexpression of p53 gene is related to tumorigenesis and development of the USC.───PTEN突变和表达缺失与宫内膜样癌的发生、发展有关。 p53基因突变和过表达与宫内膜浆液性癌发生发展关系密切。

42 、Positive Relationship of p53 and p21 Overexpression in Lymph Node Metastasis Propensity in Patients with Gastric Cancer───P53和P21过表达与胃癌淋巴结转移呈正相关

43 、The multidrug resistance of K562/D cells can be induced by DNR which is related to the Pgp overexpression, and verapamil reversed the DNR resistance by increasing the intracellular accumulation of DNR.───DNR诱导了 K5 6 2 / D细胞的 Pgp过度表达 ,异搏定通过抑制 Pgp功能逆转了 Pgp介导的K5 6 2 / D细胞的多药耐药性

44 、pET30-Cre overexpression vector───pET30-Cre高效表达

45 、Overexpression of Pyst2 mRNA in AML predicts poor chemotherapy response───Pyst2在急性髓系白血病中的表达及其意义

46 、Overexpression of bcl-2 induced by hypoxic preconditioning may play a role in sustaining the stability of MMP.───低氧预处理诱发bcl-2高表达可能是线粒体膜电位稳定性增强的机制之一。

47 、Like other tumors, development of ovarian cancer was related with the overexpression of oncogenes and the dysfunction of tumor suppressor genes.───卵巢癌的发生与其他肿瘤一样,存在癌基因的过表达与抑癌基因的失活。

48 、CD7+ CD56 + AML might constitute a distinct biologic and clinical disease entity. Our data showed that CD7+CD56+ AML associated with less anemia, overexpression of PgP and CD34 and a high incidence of central nervous system involvement.───CD7+CD56+AML具有独特的临床生物学特征,较少贫血,高表达PgP和CD34,常伴有中枢神经系统浸润。

49 、One of the possible mechanism involved in perinatal of ICP is apoptosis caused by overexpression of bax in syncytiotrophoblast leading placental dysfunction.───ICP患者**合体滋养细胞bax基因过度表达,**细胞凋亡率升高,影响**功能,可能是ICP并发围生儿缺氧的病理生理基础之一。

50 、5 Tang RF, Itakura J, Aikawa T, Matsuda K, Fujii H, Korc M, Matsumoto Y. Overexpression of lymphangiogenic growth───4李志伟,冯玉泉,顾万清,周宁新,张文智,黄志强.胰头癌外科疗效的临床分析.中华肝胆外科杂志2006;12:92-94

51 、The Amplication and Overexpression of TRIO and its Correlation with Carcinogenesis and Bladder Cancer Growth───使用组织微阵列对浸润性膀胱癌癌基因的研究

52 、Effects of Smac Gene Overexpression on Chemotherapeutic Sensitivity of Gastric Cancer Cell Line MKN-45───Smac基因过表达对胃癌细胞株MKN-45化疗敏感性的影响

53 、Atherosclerosis ;Proteins ;overexpress ;Acid lipase ;lysosomal ;───动脉粥样硬化 ;

54 、none - overexpression ErbB2 breast cancer───ErbB2非过表达乳腺癌

55 、Comparative proteome analysis of AspC gene overexpression in E.coli BL21───AspC基因导入前后E·coli BL21蛋白质组的解析

56 、A case control study on relationship between overexpression of P53 protein and esophageal carcinoma in Linxian───P53蛋白高表达与林县食管癌关系的病例对照研究

57 、P gp and LRP sometimes had co overexpression in glioma tissues.───P gp和LRP在人脑胶质瘤中有共同表达。

58 、The lose of APC or bcl-2 and c-met gene overexpression are contributed to the occurance and development of GC.───APC基因的失活、bcl-2和c-met基因的过表达对胃癌的发生、发展起促进作用;

59 、Additionally, ITK was required for efficient HIV transcription, and overexpression of ITK increased both viral transcription and virus-like particle formation.───但由于艾滋病病毒变异速度快，容易对某种特定疗法产生抗性，因此迄今没有诞生能治愈艾滋病的疗法。

60 、Different phenotypes of P68 between tumouric cell li nes (HeLa, TC 3H 10) and non-tumouric cell lines (NIH3T3 and NC 3H 10 ) were observed, and we reasoned that overexpression of P68 might profoundly a ffect cellular growth properties.───以前的工作表明P68核蛋白在同一细胞系不同生长阶段的表型不同。 它在肿瘤细胞 (HeLa和TC3H10 )与非肿瘤细胞 (NIH3T3和NC3H10 )之间表型亦有明显差异。

61 、There were no correlation between p-gp and blc-2.Conclusion Overexpression of bcl-2 or p-gp could result in poor prognosis of AL.───P gp和Bcl 2表达无相关性。 结论 P gp和Bcl 2高表达均预示AL预后不良。

62 、Uncoupling Protein 4 Overexpression Promotes Proliferation and Inhibits Apoptosis and Differentiation of Preadipocytes [A];───中华医学会第十四次全国儿科学术会议论文汇编 [C];

63 、The overexpression of p53 and bcl 2 proteins may be involved in tumorigenesis and be correlated with the differentiation of NPSC. These will help identify the prognosis of NPSC.───p5 3和bcl 2蛋白均参与鼻咽鳞癌的发生与分化 ,其表达水平的不同有助于预后判断 ;

64 、BAFF overexpression or deficiency can destroy B-cell homeostasis and induce autoimmu...───BAFF的缺陷或过量表达均能引起机体的免疫失衡,从而诱发多种疾病。

65 、AKT2 overexpression in GA may promote lymph node metastasis and progression of the disease.───AKT2的过表达可能参与了GA的淋巴结转移和病程进展;

66 、Relation of C erbB2 and Ki 67 overexpression to growth and proliferation of tumor cells in breast cancer───乳腺癌中C-erbB-2和Ki-67过度表达与癌细胞生长、增殖的关系

67 、Overexpression or functional abnormality of membrane drug transport proteins of ATP-binding cassette(ABC)family which results in an increased drug efflux,could be one of the main mechanisms.───其中,肿瘤细胞膜上ATP结合盒(ABC)转运蛋白的表达或功能异常是肿瘤细胞产生MDR的重要机制之一。

68 、Overexpression of cyc lin D1 and cdk4 were revealed in these samples and p16 was undertectable.───p16在卵巢癌中低表达 ,cyclinD1和cdk4过度表达 ;

69 、Overexpression of MUC5AC,MUC5B and MUC2 have been described in asthma secretions,Inflammatory mediators linked to asthma also take part in the regulation of mucus hypersecretion.───哮喘患者分泌的黏液中主要表现为MUC5AC、MUC5B和MUC2的过度表达,哮喘相关的炎性介质也参与了哮喘黏液高分泌的调控。

70 、Inducible overexpression of Bak sensitizes HCC-9204 cells to apoptosis induced by doxorubicin───可诱导型及Bak基因过度表达对多柔比星诱导HCC-9204细胞凋亡的增敏作用(英文)

71 、Cyclin E overexpression was associated with the histological type of EC, being more frequent in non-endometrioid endometrial carcinomas (NEECs, 5 out of 5 case) than in ECs (18 out of 38, 47.37%) (P=0.035).───cyclin E蛋白与子宫内膜癌的组织学类型、分级以及肌层浸润深度显著相关:其在子宫内膜样癌和非内膜样癌中**率分别为47.37%和5/5,两者之间比较差异具有统计学意义(P

72 、The MPG overexpression HOS cells were significantly more sensitive to the DNA damage agents, including MMS, MNNG, and TMZ, with changes in the IC50 of 6.0, 4.5, and 2.5 fold respectively.───MPG过表达HOS显著地提高DNA损伤性化疗药物MMS、MNNG和TMZ的敏感性,其半数抑制浓度(IC50)值分别下降了6·0、4·5和2·5倍。

73 、Patients with MMP-9 or TIMP-1 overexpression lived significantly shorter than those have low MMP-9 or TIMP-1 expression.───MMP-9与TIMP-1是NSCLC患者重要的临床预后判断指标，低表达者生存期长于高表达者；

74 、The sensitivity of AML cells with Pgp overexpression to cytarabine(AraC) and daunorubicin(DNR) was significantly lower than that of AML cells with Pgp lower level expression(P───Pgp高表达的AML细胞对阿糖胞苷(AraC)和柔红霉素 (DNR)药物敏感性低于低水平表达者 (P

75 、The incidences of overexpression of p 53 and C erbB 2,C ras,C myc were 56%(14/25),56%(14/25),48%(12/25),48%(12,25),respectively.───25例卵巢粒层细胞瘤中p53、C－erbB2、C－ras、C－myc的过度表达率分别为56%、56%、48%、48%。

76 、Overexpression of Bak gene may lead to apoptosis in hepatocellular carcinoma───Bak基因过表达诱导肝癌细胞凋亡

77 、TRAIL combined with Herceptin can effectively inhibit breast cell lines SKBR-3 even these cells are resistant to TRAIL alone,which may be a new therapeutic method for treatment of C-erbB2 overexpression breast cancer.───乳腺癌SKBR-3细胞株对TRAIL不敏感,但TRAIL与Herceptin联用可增加抗肿瘤作用,可能成为一种对C-erbB2过表达乳腺癌的新的治疗方法。

78 、However, in HCC with Fas expression, the ratio of apoptosis increased significantly and PCNA-LI remained, it means that the apoptosis could be promoted by the overexpression of Fas.───FaS**HCC细胞凋亡指数显著增高，而PCNA一LI改变不显著，提示Fas蛋白过度表达可促进HCC的细胞凋亡，而对其细胞增殖可能影响不大。

79 、Keywords Cadmium stress;zinc stress;ascorbate peroxidase;gene overexpression;transgenic ric;───关键词镉胁迫;锌胁迫;抗坏血酸过氧化物酶;基因过量表达;转基因水稻;

80 、Overexpression of PML growth suppressor suppresses growth and tumorigenicity of prostatic cancer cells───PML生长抑制因子过表达抑制前列腺癌细胞生长和致瘤能力的实验研究

在生物实验上的分组中kd或ko或oe是什么意思？

oe overexpressionkd knockdowm ko knockout

在生物实验上的分组中kd或ko或oe是什么意思？

在生物学中,kD表示分子量的单位道尔顿,一般写的是Da,kDa就是1000Da;Kd则表示解离平衡常数。